In early trading on Wednesday, shares of AstraZeneca topped the list of the day’s best performing components of the Nasdaq 100 index, trading up 6.4%. Year to date, AstraZeneca registers a 24.6% gain.

And the worst performing Nasdaq 100 component thus far on the day is Netflix, trading down 2.3%. Netflix is showing a gain of 31.4% looking at the year to date performance.

Two other components making moves today are Marvell Technology, trading down 2.3%, and Regeneron Pharmaceuticals, trading up 4.9% on the day.

VIDEO: Nasdaq 100 Movers: NFLX, AZN